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After more than 30 years of marriage, Jane (Kathy Bates) and Michael Stern (Robin Thomas) have reached a standstill in their private life and joint career as a successful writing team. Michael, a former alcoholic, has taken a new, self-empowered direction, leaving Jane to micro-manage no one but herself, and it scares the life out of her. So do her ailments: debilitating depression, uncontrollable panic attacks and hypochondria. Kicking her 'mid-life event' to the curb, she decides to take control of her life — by taking it an all-new direction.
Jane's life-altering adventure begins when she becomes a volunteer emergency medical technician. When her boot-camp drill-instructor promises speeding ambulances, bone-jarring rides in a small cabin, broken bodies, race-against-time illnesses, injuries and sickness, Jane knows it’s not going to be easy, but the challenge is irresistible. What unfolds is an inspiring story, based on real-life events, of a remarkable and brave woman who, in helping others, discovered a way to finally help herself.